diff --git a/src/resolve/resolved-etc-hosts.c b/src/resolve/resolved-etc-hosts.c
index e6bf20db54..c2839d425a 100644
--- a/src/resolve/resolved-etc-hosts.c
+++ b/src/resolve/resolved-etc-hosts.c
@@ -37,6 +37,8 @@ void etc_hosts_free(EtcHosts *hosts) {
 void manager_etc_hosts_flush(Manager *m) {
         etc_hosts_free(&m->etc_hosts);
         m->etc_hosts_mtime = USEC_INFINITY;
+        m->etc_hosts_ino = 0;
+        m->etc_hosts_dev = 0;
 }
 
 static int parse_line(EtcHosts *hosts, unsigned nr, const char *line) {
@@ -224,8 +226,9 @@ static int manager_etc_hosts_read(Manager *m) {
                         return 0;
                 }
 
-                /* Did the mtime change? If not, there's no point in re-reading the file. */
-                if (timespec_load(&st.st_mtim) == m->etc_hosts_mtime)
+                /* Did the mtime or ino/dev change? If not, there's no point in re-reading the file. */
+                if (timespec_load(&st.st_mtim) == m->etc_hosts_mtime &&
+                    st.st_ino == m->etc_hosts_ino && st.st_dev == m->etc_hosts_dev)
                         return 0;
         }
 
@@ -249,6 +252,8 @@ static int manager_etc_hosts_read(Manager *m) {
                 return r;
 
         m->etc_hosts_mtime = timespec_load(&st.st_mtim);
+        m->etc_hosts_ino = st.st_ino;
+        m->etc_hosts_dev = st.st_dev;
         m->etc_hosts_last = ts;
 
         return 1;
diff --git a/src/resolve/resolved-manager.c b/src/resolve/resolved-manager.c
index 4f72077720..df25907a4c 100644
--- a/src/resolve/resolved-manager.c
+++ b/src/resolve/resolved-manager.c
@@ -591,6 +591,8 @@ int manager_new(Manager **ret) {
                 .need_builtin_fallbacks = true,
                 .etc_hosts_last = USEC_INFINITY,
                 .etc_hosts_mtime = USEC_INFINITY,
+                .etc_hosts_ino = 0,
+                .etc_hosts_dev = 0,
                 .read_etc_hosts = true,
         };
 
diff --git a/src/resolve/resolved-manager.h b/src/resolve/resolved-manager.h
index 7f7d3a6b9c..446f258b49 100644
--- a/src/resolve/resolved-manager.h
+++ b/src/resolve/resolved-manager.h
@@ -127,6 +127,8 @@ struct Manager {
         /* Data from /etc/hosts */
         EtcHosts etc_hosts;
         usec_t etc_hosts_last, etc_hosts_mtime;
+        ino_t etc_hosts_ino;
+        dev_t etc_hosts_dev;
         bool read_etc_hosts;
 
         /* Local DNS stub on 127.0.0.53:53 */